Portrayed a nerdy lab-technician who erases people's unpleasent memories in Michel Gondry's "Eternal Sunshine of the Spotless Mind"
Portrayed a San Francisco detective in David Fincher's thriller, "Zodiac"
Received critical acclaim for his work in Kenneth Lonergan's "Betrayal By Everyone"
Co-starred with Julianne Moore and Annette Bening in "The Kids Are All Right," about two children conceived by artificial insemination who invite their birth father (played by Ruffalo) into their home
Co-starred in the Marvel superhero ensemble feature "The Avengers" as Bruce Banner/The Hulk
Co-starred in dramedy "Begin Again"
Cast alongside Steve Carell and Channing Tatum in biopic "Foxcatcher"
Co-starred in the from-life drama "Spotlight"
Co-starred as Hulk in Taika Waititi's irreverent "Thor: Ragnarok"
Returned as Hulk yet again in "Avengers: Infinity War"
Played the mother's boyfriend in Spike Jonze's live-action adaptation of Maurice Sendak's children's book, "Where the Wild Things Are"
Re-teamed with Lonergan for "You Can Count on Me" playing Laura Linney's troubled, aimless drifter brother
Cast as a prisoner operating as a bookmaker in "The Last Castle"
Co-starred with Ethan Hawke in the crime drama, "What Doesn't Kill You"
Co-starred with Julianne Moore in Fernando Meirelles' "Blindness"
Co-starred with Mary Stuart Masterson in the Lifetime holiday movie "On the 2nd Day of Christmas"
Appeared in "There Goes My Baby" starring Dermot Mulroney and Rick Schroder
Co-starred with Adrien Brody, as brother who make a living off of swindling millionaires, in the comedy "The Brothers Bloom"
Featured in the John Woo-directed "Windtalkers"
Had a featured role as a safecracker in the independent comedy "Safe Men"
Had a featured role as the illusionist's brother Theo in TNT's biopic "Houdini"
Played Jennifer Aniston's boyfriend in the comedy "Rumor Has It...," directed by Rob Reiner
Reprised role of Warren Straub in an Off-Broadway run of "This Is Our Youth"
Starred as Warren Straub in Kenneth Lonergan's production of "This Is Our Youth"
Cast in Steven Zaillian's big-screen adaptation of the Robert Penn Warren novel "All the King's Men"
Earned a Tony nomination for his performance in the Broadway production of "Awake and Sing"
Played a divorced lawyer who accidentally kills a child and speeds away, in Terry George's film "Reservation Road"
Played a U.S. Marshal in Martin Scorsese's "Shutter Island"
Starred in the independent feature "XX/XY"
Appeared in episodes of the short-lived series "Middle Ages" (NBC)
Co-starred with Meg Ryan in the thriller "In The Cut"
Co-wrote, co-produced and acted in the independent release "The Destiny of Marty Fine"
Featured alongside real-life husband and wife Jerry Stiller and Anne Meara in the comedy "A Fish in a Bathtub"
Had a featured role in Dan Zukovic's popular culture satire "The Last Big Thing"
Played a cop in Michael Mann's thriller "Collateral," starring Tom Cruise and Jamie Foxx
Featured in the hit crime comedy "Now You See Me"
Reprised role of the Hulk in "Avengers: Age of Ultron"
Reprised role of Dyan Rhodes in "Now You See Me 2"
Co-starred with Naomi Watts, Laura Dern and Peter Krause in "We Don't Live Here Anymore"
Made stage debut in David Steen's "Avenue A" at Los Angeles' Cast Theater