Featured as a photojournalist who disappears in the former Yugoslavia in the festival-screened drama "Harrison's Flowers"
Gave an effective performance as Sigourney Weaver's farmer husband in "A Map of the World"
Grew up in the San Francisco Bay area
Off-Broadway debut, "Blue Plate Special"
Played a blind, brilliant computer hacker in "Sneakers" opposite Robert Redford and Sidney Poitier
Played Helen Keller's father in the ABC remake of "The Miracle Worker"
Played the brain surgeon in HBO's appeal for gun control "The James Brady Story"
Played the father in the fantasy film "The Spiderwick Chronicles"
Played the leader of a secret operation who's mission is to hunt down Jason Bourne (Matt Damon) in "The Bourne Ultimatum"
Portrayed the morally upright Constable Hatfield in Sayles' "Matewan"
Portrayed Tom Cruise's jailbird brother in the film adaptation of John Grisham's novel "The Firm"
Reunited with Jessica Lange for "Losing Isaiah"
Reunited with Sayles to play a fisherman who romances a lounge singer (Mary Elizabeth Mastrantonio) in "Limbo"
Starred alongside Stockard Channing in the Lincoln Center production of Tom Stoppard's play "Hapgood"
Worked with Sayles in a summer theater company in New Hampshire
Appeared as Wesley in Mike Nichols' "Silkwood"
Appeared in the TNT adaptation of Arthur Miller's stage play "The American Clock"
Cast in the HBO original film "The Notorious Bettie Page," starring Gretchen Mol as the 1950s pin-up model
Co-starred in the dramatic thriller "Fracture" as the district attorney opposite Anthony Hopkins
Delivered a compelling interpretation of the morally flawed baseball pitcher Eddie Cicotte in Sayles' "Eight Men Out"
Had regular role on the short-lived CBS police drama "Big Apple"
Met John Sayles while attending Williams College
Portrayed J. Robert Oppenheimer in CBS's "Day One"
TV series debut, "The Days and Nights of Molly Dodd" (NBC/Lifetime) as the Moss, the eccentric bookstore owner
Appeared as the wealthy procurer Pierce Patchett in "L.A. Confidential"
Co-starred in Roundabout Theatre Company's production of Samuel Beckett's "Waiting for Godot"
Played an extraterrestrial bounty hunter alongside John Sayles in Sayles' "The Brother From Another Planet"
Played a dynamic adman in "A League of Their Own"
Played the emotionally remote father of a son coping with AIDS in "In the Gloaming" (HBO), helmed by Christopher Reeve
Portrayed a realistic street person for Sayles' "City of Hope"
Portrayed journalist Edward R. Murrow, who scrutinized Sen. Joseph McCarthy's communist witch hunt in George Clooney's "Good Night, and Good Luck"; earned Oscar, Independent Spirit Award, Golden Globe and SAG nominations for Best Actor
Portrayed Theseus in Michael Hoffman's adaptation of "William Shakespeare's A Midsummer Night's Dream"
Made stage debut in "Einstein and the Polar Bear" at Connecticut's Hartford Stage
Starred opposite Jessica Lange in the Hallmark Hall of Fame presentation of "O Pioneers!" (CBS)
Toured for six months with Ringling Brothers and Barnum & Bailey Circus as a replacement for half of the Siamese-twin clown
Was part of the all-star cast of the Roundabout Theater's revival of "Three Sisters"
Acted opposite Meryl Streep in "The River Wild"
Cast as the Reverend Russell in "Simon Birch"
Earned a Grammy nomination for Best Spoken Word for the album <i>The Lincoln-Douglas Debates</i>
Film debut, "The Return of the Secaucus Seven" directed by Sayles
Helped start a children's theater in Glen Falls, NY
Played a mysterious man who meets an equally odd woman (Kyra Sedgwick) on a plane in Craig Lucas' stage play "Stranger"
Proved himself a capable romantic lead in Sayles' "Passion Fish"
Returned to Broadway in support of Ian McKellen and Helen Mirren in "The Dance of Death"
TV debut, guest appearance on an episode of "Miami Vice" (NBC)
Featured in the Sundance-screened "Blue Car"
Worked in children's theater and summer stock
Co-starred opposite Claire Danes in "Temple Grandin"; earned an Emmy nomination for Outstanding Supporting Actor in a Miniseries or Movie
Starred as King Alonzo in the Julie Taymor directed adaptation of Shakespeare's "The Tempest"
Nominated for the 2011 Golden Globe Award for Best Performance by an Actor in a Supporting Role in a Series, Mini-Series or Motion Picture Made for Television ("Temple Grandin")
Nominated for the 2010 Primetime Emmy Award for Outstanding Supporting Actor in a Miniseries or a Movie ("Temple Grandin")
Reprised role in "The Bourne Legacy"
Portrayed U.S. Secretary of State William Seward opposite Daniel Day-Lewis in Steven Spielberg's "Lincoln"
Had a minor role in "Godzilla" reboot