Co-starred with Johnny Depp in "From Hell," playing an Irish prostitute targeted by Jack the Ripper
Had romantic lead opposite one-time boyfriend Edward Burns in "Sidewalks of New York"
Starred as an attending psychiatrist in a nine-episode guest-starring role on NBC's "Scrubs"
Appeared in the CBS TV-movie "O Pioneers!" as a young version of Jessica Lange's character Alexandra Bergson
Cast as a slightly dizzy blonde who falls in love with a man she later comes to think is her long-lost brother in the oddball comedy "Say It Isn't So"
Cast as Judy Robinson in the feature version of "Lost in Space"
Co-starred in the romantic comedy "The Guru"
Gave an acclaimed co-starring performance in Gus Van Sant's "Drugstore Cowboy"
Had leading role opposite Robert Downey Jr and Natasha Gregson Wagner in "Two Girls and a Guy"
Played a heroin addict opposite Jeremy Sisto in the indie film "Broken"
Plays a woman who falls for her brother's fiancé in "Gray Matters"
Starred as an abandoned wife on a mission to find and reclaim her husband in the road movie "Committed"
Starred in the direct-to-video release "Toughguy/Terrified"
Starred in the independent drama "Desert Winds"
Was featured as half of a Midwestern couple taken in by con man Will Smith in "Six Degrees of Separation"
Appeared in "Mrs. Parker and the Vicious Circle"
Played a parole officer in "Guilty as Charged"
Played Drew Barrymore's character in "Stab," the film-within-a-film featured in "Scream 2"
Reteamed with Van Sant for the poorly received "Even Cowgirls Get the Blues"
Appeared opposite Joseph Fiennes in the erotically charged romance "Killing Me Softly"
Co-starred in "Diggstown," a film starring James Woods and Louis Gossett Jr billed as "Rocky" meets "The Sting"
Had a featured role in the 1950s set musical "Shout"
Made her television series debut in the short-lived "Emily's Reasons Why Not" (ABC); show aired only one episode
Played Aunt Opal in "Judy Moody and the Not Bummer Summer," a film adaptation of the popular <i>Judy Moody</i> book series
Reprised role from "The Hangover" in "The Hangover Part III"
Co-starred with Rob Schneider in animated comedy "Norm of the North"
Played Tilly on Flaked
Guest starred on two episodes of "Growing Pains" (ABC)
Reprised role of Annie in the feature "Twin Peaks: Fire Walk with Me"
Co-starred in the Todd Phillips-directed comedy "The Hangover"
Had regular role of Annie, a former nun involved with Kyle MacLachlan's Agent Cooper, on the ABC series "Twin Peaks"
Starred opposite the "Two Coreys" in teen comedy "License to Drive"
Co-starred as 1960s CIA agent Felicity Shagwell in the sequel "Austin Powers: The Spy Who Shagged Me"
Offered memorable supporting turn as Jon Favreau's dream girl in "Swingers"
Was featured as an ambitious starlet in "Bowfinger," a Hollywood satire starring Steve Martin and Eddie Murphy
Cast as Rollergirl, a teenaged member of the extended family of adult film actors, in Paul Thomas Anderson's celebrated "Boogie Nights"
Co-starred with James Franco in the porn-industry drama "About Cherry"
Had a recurring role as Julia on "Californication"
Appeared as Annie in "Twin Peaks: The Missing Pieces," a feature-length assembly of unused footage from "Twin Peaks: Fire Walk With Me"
Starred in dark comedy "My Dead Boyfriend"
Had the recurring role of Diane Duran on "Angie Tribeca"
Starred in crime thriller "Wetlands"