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The working titles of this film were Two Sisters from Seattle and Those Sisters from Seattle. Although the picture was shot in 3-D, the viewed print was in standard format. As noted by reviews, the film was the first 3-D, stereo musical. Cynthia and Kay Bell, who played "Connie Edmonds" and "Nell Edmonds," respectively, were billed onscreen as The Bell Sisters. Popular singers Guy Mitchell and Teresa Brewer made their feature-film debuts in the picture; Those Redheads from Seattle was the only feature film Brewer made.
According to publicity materials contained in the film's copyright record, location shooting took place in the Colorado Rockies. Hollywood Reporter news items add the following actors to the cast: Beverly Cottrell, Danny Scharf, Al Hill, Max Wagner and Ed Mitchell. Hollywood Reporter also notes that Lyle Moraine, Bob Hope's stand-in, was to make his screen debut in the picture. The appearance of these actors in the final film has not been confirmed.